Dr. El-Zein’s research focus is on understanding the role of gene-environment interactions in the risk of cancer development. She has developed expertise in the area of biomarkers and genetic susceptibility to disease. She has applied unique markers to identify several inherited genetic traits that influence human sensitivity to different cancers such as lung, breast and lymphomas. Dr. El-Zein’s laboratory has a translational research approach, and is currently studying human populations using quantitative imaging coupled with molecular biomarkers to identify unique signatures that would improve the power of cancer risk assessment models.

The results from these studies are providing new information that has significant and practical public health implications in the area of early detection and primary prevention of disease. The overall goal is to develop novel approaches to identify susceptible individuals at high risk of developing lung and breast cancers. New knowledge generated from these research endeavors are geared to fulfill the need for rapid and efficient translation of emerging new technologies and approaches for improved patient management, early detection and prevention.

Dr. El-Zein’s research focus is on understanding the role of gene-environment interactions in the risk of cancer development. She has developed expertise in the area of genotypic and phenotypic biomarkers and genetic susceptibility to disease. She has applied these unique markers to identify several inherited genetic traits that influence human sensitivity to different cancers such as lung, breast and lymphomas. Dr. El-Zein’s laboratory has a translational research approach, and is currently studying human populations using quantitative imaging coupled with molecular biomarkers to identify unique signatures that would improve the power of cancer risk assessment models. The results from these studies are providing new information that has significant and practical public health implications in the area of early detection and primary prevention of disease.